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Jerry E Stewart Selected Research

Focal Adhesion Protein-Tyrosine Kinases

6/2022Serine-Threonine Kinase Receptor Associate Protein (STRAP) confers an aggressive phenotype in neuroblastoma via regulation of Focal Adhesion Kinase (FAK).
9/2019The effects of focal adhesion kinase and platelet-derived growth factor receptor beta inhibition in a patient-derived xenograft model of primary and metastatic Wilms tumor.
1/2019Focal Adhesion Kinase Inhibition Contributes to Tumor Cell Survival and Motility in Neuroblastoma Patient-Derived Xenografts.
8/2016Targeting Focal Adhesion Kinase Suppresses the Malignant Phenotype in Rhabdomyosarcoma Cells.
6/2015Focal adhesion kinase and p53 synergistically decrease neuroblastoma cell survival.
1/2015Inhibition of FAK and VEGFR-3 binding decreases tumorigenicity in neuroblastoma.
4/2014FAK inhibition abrogates the malignant phenotype in aggressive pediatric renal tumors.
3/2014Inhibition of the focal adhesion kinase and vascular endothelial growth factor receptor-3 interaction leads to decreased survival in human neuroblastoma cell lines.
6/2013FAK inhibition decreases cell invasion, migration and metastasis in MYCN amplified neuroblastoma.
4/2013FAK Inhibition Decreases Hepatoblastoma Survival Both In Vitro and In Vivo.
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Jerry E Stewart Research Topics

Disease

28Neoplasms (Cancer)
06/2022 - 03/2007
16Neuroblastoma
06/2022 - 01/2013
9Hepatoblastoma
06/2022 - 01/2014
8Carcinogenesis
01/2022 - 04/2014
2Medulloblastoma
10/2019 - 01/2018
2Multiple Sclerosis
01/2019 - 01/2018
2Rhabdomyosarcoma
01/2018 - 08/2016
2Glioma (Gliomas)
03/2007 - 10/2005
1Brain Neoplasms (Brain Tumor)
10/2019
1Wilms Tumor (Wilm's Tumor)
09/2019
1Leukemia
02/2019
1Hepatocellular Carcinoma (Hepatoma)
04/2018
1Astrocytoma (Pilocytic Astrocytoma)
03/2007
1Skin Neoplasms (Skin Cancer)
10/2005
1Severe Combined Immunodeficiency (Bare Lymphocyte Syndrome)
02/2005
1Glioblastoma (Glioblastoma Multiforme)
02/2005

Drug/Important Bio-Agent (IBA)

11Focal Adhesion Protein-Tyrosine KinasesIBA
06/2022 - 02/2005
7Phosphotransferases (Kinase)IBA
01/2022 - 02/2005
6Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
08/2016 - 04/2013
5Proteins (Proteins, Gene)FDA Link
06/2022 - 10/2005
5Cisplatin (Platino)FDA LinkGeneric
06/2022 - 04/2018
5proto-oncogene proteins pimIBA
01/2022 - 04/2018
5Tretinoin (Retinoic Acid)FDA LinkGeneric
06/2021 - 07/2015
4Fingolimod Hydrochloride (FTY720)FDA Link
04/2022 - 01/2018
4Small Interfering RNA (siRNA)IBA
06/2021 - 06/2013
3Messenger RNA (mRNA)IBA
01/2022 - 01/2021
3AZD1208IBA
01/2021 - 04/2018
2Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA
06/2022 - 06/2021
2Protein Phosphatase 2 (Protein Phosphatase 2A)IBA
04/2022 - 01/2019
2UAB 30IBA
01/2021 - 06/2020
2RetinoidsIBA
10/2019 - 01/2016
2Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA
09/2019 - 06/2013
2Retinoid X Receptors (Retinoid X Receptor)IBA
01/2018 - 07/2015
2Vascular Endothelial Growth Factor Receptor-3 (Flt 4)IBA
01/2015 - 03/2014
2Peptides (Polypeptides)IBA
03/2014 - 03/2007
16- (4- (3- (methylsulfonyl)benzylamino)- 5- (trifluoromethyl)pyrimidin- 2- ylamino)- 3,4- dihydroquinolin- 2(1H)- oneIBA
06/2022
1CrizotinibIBA
07/2021
1Sunitinib (Sutent)FDA Link
07/2021
1Strap proteinIBA
06/2021
1GSK343IBA
01/2021
1Enhancer of Zeste Homolog 2 ProteinIBA
01/2021
1Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA
09/2019
1Immunologic Factors (Immunomodulators)IBA
01/2019
1Pharmaceutical PreparationsIBA
01/2019
1Immunosuppressive Agents (Immunosuppressants)IBA
01/2018
1chloropyramineIBA
01/2015
1Biological ProductsIBA
03/2014
1NAc- Sar- Gly- Val- (d- allo- Ile)- Thr- Nva- Ile- Arg- ProNEt (ABT 510)IBA
03/2007
1ThrombospondinsIBA
03/2007
1LDL Receptors (LDL Receptor)IBA
10/2005
1CarcinogensIBA
10/2005
1Cyclin D1IBA
02/2005
1CyclinsIBA
02/2005
1AgarIBA
02/2005

Therapy/Procedure

17Therapeutics
04/2022 - 03/2007
3Drug Therapy (Chemotherapy)
01/2021 - 01/2015
1Injections
06/2022
1Oncolytic Virotherapy
02/2022
1Radiotherapy
10/2016
1Aftercare (After-Treatment)
01/2016
1Euthanasia (Mercy Killing)
03/2007